Figure 7.

Analysis of network dynamics of D1 and D2 SPNs. The similarity index matrices of the stimulation induced by continuous (a) and stimulation in patterned pulses (b) show that continuous delivery of light activated sets of neurons with higher similarity index across stimulations, than stimulation delivered in patterned pulses. (c) Summary box plots to illustrate the significantly higher mean similarity index of vectorized activity observed with continuous versus patterned stimulation (paired t (11) = 4.24, p < 0.001, n = 12 mice). Black numbers: vector numbers; blue numbers: responses from one of the four stimulations