Table 1.
Patients' characteristics
| Age mean, y | 60.1 (range 39‐78) |
| <44 years | 11 (5%) |
| 45–54 | 43 (19%) |
| 55–64 | 115 (51%) |
| >65 | 56 (25%) |
| Gender (% male) | n (%), 120 (53%) |
| Dementia stage (GDS) | |
| GDS ≤4 (mild to moderate dementia) | 39 (17%) |
| GDS 5 (moderately severe dementia) | 55 (24%) |
| GDS 6 (severe dementia) | 68 (30%) |
| GDS 7 (very severe dementia) | 63 (28%) |
| Type of dementia | |
| Alzheimer's dementia | 72 (32%) |
| Vascular dementia | 29 (13%) |
| Frontotemporal dementia | 36 (16%) |
| Alcohol‐related dementia | 40 (18%) |
| Dementia NOS and other types of dementia | 48 (21%) |
| Neuropsychiatric symptoms | |
| NPI‐NH any significant symptoma | 202 (89.8%; CI, 85.1‐93.1) |
| Two or more significant symptoms | 167 (74.2%; CI, 68.1‐79.5) |
| NPI‐NH agitation clusterb | 149(66.2%; CI, 59.8‐72.1) |
| NPI‐NH psychosis clusterc | 25 (11.1%; CI, 7.6‐15.9) |
| CMAI any significant symptomd | 197 (87.6%; CI, 82.6‐91.2) |
Abbreviations: CI, confidence interval; CMAI, Cohen‐Mansfield Agitation Inventory; GDS, global deterioration scale; GRAD, Guidelines for the Rating of Awareness Deficits; NOS, not otherwise specified; NPI‐NH, Neuropsychiatric Inventory—Nursing Home.
a
Any item with frequency (F) × severity (S) score more than or equal to 4.
b
One or more significant symptom(s) of agitation/aggression, disinhibition, irritability, and/or aberrant motor behavior.
c
One or both significant symptoms of delusions and hallucinations.
d
Any item occurring once a week or more.