Table 2.
Healthcare workers | |||||
---|---|---|---|---|---|
Active TB | No Mtb infection | Recent LTBI | Remote LTBI | Serodiagnosis (+) | |
Number (M:F) | 15 (8:7) | 19 (5:14) | 13 (3:10) | 12 (3:9) | 15 (5:10) |
Age, y | 47 ± 18.1 (23–78) | 44 ± 9.8 (27–58) | 43 ± 10.3 (24–58) | 50 ± 6.4 (38–58) | 44 ± 7.5 (28–57) |
Antigens | Antibody titers (ΔOD) | ||||
ESAT6 | 0.49 ± 0.56 | 0.04 ± 0.02# | 0.31 ± 0.41 | 0.07 ± 0.07* | 0.04 ± 0.02$ |
CFP10 | 0.48 ± 0.49 | 0.12 ± 0.1# | 0.24 ± 0.24 | 0.24 ± 0.24 | 0.21 ± 0.16 |
Acr | 0.84 ± 0.51 | 0.15 ± 0.07# | 0.38 ± 0.28* | 0.26 ± 0.15# | 0.25 ± 0.18$ |
MDP1 | 1.52 ± 0.86 | 0.27 ± 0.12# | 0.86 ± 0.43* | 0.33 ± 0.15# | 0.38 ± 0.13# |
Ag85A | 1.93 ± 0.87 | 0.76 ± 0.29# | 1.01 ± 0.87* | 1.02 ± 0.44$ | 0.91 ± 0.47& |
QFT‐Gold | (‐):15, ( ± ):4, ( + ):0 | (‐):0, ( ± ):0, ( + ):13 | (‐):0, ( ± ):0, ( + ):12 | (‐):13, ( ± ):2, ( + ):0 | |
TBGL (unit/mL) | 0.20 ± 0.34 | 1.62 ± 2.06 | 1.88 ± 2.59 | 5.08 ± 6.44 | |
LAM | (‐):19, ( + ):0 | (‐):9, ( + ):4 | (‐):9, ( + ):3 | (‐):5, ( + ):10 | |
GPL‐core (unit/mL) | 0.01 ± 0.02 | 0.05 ± 0.05 | 0.01 ± 0.01 | 0.03 ± 0.03 |
Abbreviations: ΔOD, optical density (average ± SD); M:F, male:female.
P‐values between active TB and other groups:
ESAT6 (#: P = 0.0006, *: P = 0.0071, $: P = 0.0014)
CFT10 (#: P = 0.0033).
Acr (#: P < 0.0001, *: P = 0.0005)
MDP1 (#: P < 0.0001, *: P = 0.0015)
Ag85A (#: P < 0.0001, *: P = 0.0017, $: P = 0.0027, &: P < 0.0001)