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. 2019 Apr 9;63(3-4):130–138. doi: 10.1111/1348-0421.12674

Table 2.

Comparison of IgG antibody titers against M. tuberculosis (Mtb) antigens between healthcare workers and patients with active TB

Healthcare workers
Active TB No Mtb infection Recent LTBI Remote LTBI Serodiagnosis (+)
Number (M:F) 15 (8:7) 19 (5:14) 13 (3:10) 12 (3:9) 15 (5:10)
Age, y 47 ± 18.1 (23–78) 44 ± 9.8 (27–58) 43 ± 10.3 (24–58) 50 ± 6.4 (38–58) 44 ± 7.5 (28–57)
Antigens Antibody titers (ΔOD)
ESAT6 0.49 ± 0.56 0.04 ± 0.02# 0.31 ± 0.41 0.07 ± 0.07* 0.04 ± 0.02$
CFP10 0.48 ± 0.49 0.12 ± 0.1# 0.24 ± 0.24 0.24 ± 0.24 0.21 ± 0.16
Acr 0.84 ± 0.51 0.15 ± 0.07# 0.38 ± 0.28* 0.26 ± 0.15# 0.25 ± 0.18$
MDP1 1.52 ± 0.86 0.27 ± 0.12# 0.86 ± 0.43* 0.33 ± 0.15# 0.38 ± 0.13#
Ag85A 1.93 ± 0.87 0.76 ± 0.29# 1.01 ± 0.87* 1.02 ± 0.44$ 0.91 ± 0.47&
QFT‐Gold (‐):15, ( ± ):4, ( + ):0 (‐):0, ( ± ):0, ( + ):13 (‐):0, ( ± ):0, ( + ):12 (‐):13, ( ± ):2, ( + ):0
TBGL (unit/mL) 0.20 ± 0.34 1.62 ± 2.06 1.88 ± 2.59 5.08 ± 6.44
LAM (‐):19, ( + ):0 (‐):9, ( + ):4 (‐):9, ( + ):3 (‐):5, ( + ):10
GPL‐core (unit/mL) 0.01 ± 0.02 0.05 ± 0.05 0.01 ± 0.01 0.03 ± 0.03

Abbreviations: ΔOD, optical density (average ± SD); M:F, male:female.

P‐values between active TB and other groups:

ESAT6 (#: P = 0.0006, *: P = 0.0071, $: P = 0.0014)

CFT10 (#: P = 0.0033).

Acr (#: P < 0.0001, *: P = 0.0005)

MDP1 (#: P < 0.0001, *: P = 0.0015)

Ag85A (#: P < 0.0001, *: P = 0.0017, $: P = 0.0027, &: P < 0.0001)