Skip to main content
. Author manuscript; available in PMC: 2019 Sep 30.
Published in final edited form as: J Trauma Acute Care Surg. 2019 Apr;86(4):617–624. doi: 10.1097/TA.0000000000002177

Figure 2. TXA suppresses the release of mtDNA to mouse bloodstream induced by severe burn.

Figure 2.

Mice received intraperitoneal injection of TXA immediately after undergoing burning procedure. A group of mice received both TXA injection and topical p38 MAPK inhibitor. Mean and SD of mtDNA plasma content are shown. The mean of the control (sham) group was taken as a reference (100%) and used to divide all the means by. The statistical significance of differences between sham (N=8) and burn (N=9), burn and burn + TXA (N=10), and burn + TXA and burn +TXA + p38 MAPK inhibitor (N=10) groups was determined using t-test with Welch correction.