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miR-145 sensitized ESCC to DDP through inhibiting AKT3. a Cell viability was detected by MTT assay in EC109 and KYSE-30 cells exposed to DDP after transfection with miR-145 mimics, sh-AKT3, or miR-145 mimcis + pcDNA3.1-AKT3. b Analysis and quantifications of DDP IC50 value. All the results were shown as mean ± SD (n = 3), which were three separate experiments performed in triplicate. *p < 0.05 and **p < 0.01
