Table 2.
Baseline Demographics of HD Patients Split by the Presence of Atrial Fibrillation.
| No AF | AF | All | P value | |
|---|---|---|---|---|
| n | 5073 | 429 | 5502 | |
| Median age (IQR), years | 64.6 [23.9] | 70.9 [15.8] | 65.1 [23.3] | <.0001 |
| Female (%) | 2114 [41.67] | 157 [36.6] | 2271 [41.3] | .04 |
| Primary renal diagnosis (%) | ||||
| Glomerulonephritis | 729 [14.4] | 63 [14.7] | 792 [14.4] | .83 |
| Interstitial disease | 1081 [21.3] | 76 [17.7] | 1157 [21.0] | .08 |
| Multisystem | 1245 [24.5] | 111 [25.9] | 1356 [24.7] | .56 |
| Diabetes | 1104 [21.8] | 79 [18.4] | 1183 [21.5] | .11 |
| Other | 907 [17.9] | 97 [22.6] | 1004 [18.3] | .02 |
| Missing | 7 [0.1] | 3 [0.7] | 10 [0.2] | |
| Urban rurality status (%) | ||||
| Urban | 770 [15.2] | 57 [13.3] | 827 [15.0] | |
| Rural | 4303 [84.8] | 372 [86.7] | 4675 [85.0] | .32 |
| Deprivation status (%) | ||||
| Least (SIMD quintiles 3-5) | 3672 [72.4] | 309 [72.0] | 3981 [72.4] | |
| Most (SIMD quintiles 1 and 2) | 1401 [27.6] | 120 [28.0] | 1521 [27.6] | .87 |
| Past medical history (%) | ||||
| AF | 0 | 429 [100] | 429 [7.8] | <.0001 |
| Ischemic heart disease | 1678 [33.1] | 234 [54.6] | 1912 [34.8] | <.0001 |
| Stroke | 193 [3.8] | 40 [9.3] | 233 [4.2] | <.0001 |
| Diabetes | 1773 [35.0] | 147 [34.3] | 1920 [34.9] | .79 |
| Hypercholesterolemia | 679 [13.4] | 66 [15.4] | 745 [13.5] | .27 |
| Obesity | 339 [6.7] | 38 [8.9] | 377 [6.9] | .07 |
| Smoking | 314 [6.2] | 17 [4.0] | 331 [6.0] | .07 |
| Hypertension | 3575 [70.5] | 345 [80.4] | 3920 [71.3] | <.0001 |
| Clinical variables, median (IQR) | ||||
| SBP, mm Hg | 139.0 [29.0] | 132.3 [31.8] | 138.5 [29.0] | <.0001 |
| DBP, mm Hg | 71.0 [19.0] | 68 [18.3] | 71 [18.5] | <.01 |
| Weight, kg | 72.6 [23.8] | 72.8 [22.0] | 72.6 [23.6] | .92 |
| Use of ESA | 3765 [74.2] | 277 [64.6] | 4042 [73.5] | <.0001 |
| Laboratory variables, median (IQR) | ||||
| Hemoglobin, g/dL | 11.4 [1.8] | 11.5 [1.8] | 11.4 [1.8] | .15 |
| Serum albumin, g/L | 37.0 [7.0] | 36.5 [7.0] | 37.0 [7.0] | .05 |
| Serum phosphate, mmol/L | 1.47 [0.56] | 1.50 [0.54] | 1.47 [0.56] | .02 |
| Serum adjusted calcium, mmol/L | 2.35 [0.19] | 2.36 [0.21] | 2.36 [0.20] | .71 |
| Urea reduction ratio | 71.5 [9.0] | 70 [9] | 71.5 [8.5] | .13 |
| Stroke cases | 318 [6.3] | 45 [10.5] | 363 [6.6] | <.01 |
| Death at follow-up | 3087 [60.9] | 393 [91.6] | 3480 [63.3] | <.0001 |
Note. Mann-Whitney U or chi-square test is applied, when comparing HD with transplant and PD with transplant. AF = atrial fibrillation; IQR = interquartile range; SIMD = Scottish Index of Multiple Deprivation; SBP = systolic blood pressure; DBP = diastolic blood pressure; ESA = erythropoietin-stimulating agent; HD = hemodialysis.