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. 2019 May 10;1447(1):110–118. doi: 10.1111/nyas.14108

Figure 1.

Figure 1

Origin of germ‐line genome architecture in ciliates. (A) Invasion of a transposable element into the germ‐line genome at a target insertion site (red boundaries, germline). (B) Over time, it proliferates (bloom) throughout the germ‐line genome. (C) These TEs decay over time into internally eliminated sequences (IESs), ultimately generating the traditional nonscrambled genome architecture. The original insertion target sequences (red) remain as pointer sequences that guide MDS organization in many ciliates (e.g., Paramecium and Euplotes).