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. 2019 Jun 28;28(9-10):1271–1278. doi: 10.1177/0963689719860840

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© The Author(s) 2019

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Fig. 1. — Adipose-tissue-derived MSCs from MetS pigs release smaller vesicles. (A) Representative size distribution curve by NTA. (B)–(C). Overall concentration of secreted vesicles in Lean and MetS pigs using NTA and flow cytometry, with EV stained with Tag-it-Violet^™, tracking dye. (D)–(F). Average vesicle size (NTA), electron microscopy images showing diameter, and percentage of vesicles separated into size increments to show size distribution in Lean- and MetS-EV. *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.005 (vs. Lean).