Skip to main content
. Author manuscript; available in PMC: 2019 Sep 30.
Published in final edited form as: Eur J Pharmacol. 2019 Jan 25;848:131–139. doi: 10.1016/j.ejphar.2019.01.037

Fig. 5. Inverse agonist sensitization of the 5-HT2C receptor.

Fig. 5.

Cells expressing the 5-HT2C receptor were treated with 1 μM inverse agonist for 20 h, washed, then re–stimulated with 5-HT (1–10,000 nM). n = 3; ** = P < 0.01 compared to control; *** = P < 0.001 compared to control; ****= P < 0.0001 compared to control; + = P < 0.05 compared to SB 206553–induced sensitization; ++ = P < 0.01 compared to SB 206553–induced sensitization; +++ = P < 0.001 compared to SB 206553–induced sensitization, via one-way ANOVA.