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. Author manuscript; available in PMC: 2019 Sep 30.
Published in final edited form as: Eur J Pharmacol. 2019 Jan 25;848:131–139. doi: 10.1016/j.ejphar.2019.01.037

Table 1.

5-HT2C agonists pEC50 and Emax values, relative to 5-HT: Inositol phosphate production.

Agonist pEC50 Emax (% 5-HT)
5-HT 8.12 ± 0.10 100 ± 6
WAY-161503 8.07 ± 0.08 100 ± 2
lorcaserin 8.20 ± 0.15 100 ± 1
Ro 60–0175 8.30 ± 0.05 99 ± 6
mCPP 7.41 ± 0.21a 88 ± 10
DOI 8.32 ± 0.10 82 ± 4
MBP 7.76 ± 0.04 73 ± 4a
PAT 8.01 ± 0.14 50 ± 1a
aripiprazole 6.28 ± 0.30a 40 ± 4a

n = 3 or 4.

a

= P < 0.05 different from 5-HT via one-way ANOVA.