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. Author manuscript; available in PMC: 2019 Sep 30.
Published in final edited form as: Eur J Pharmacol. 2019 Jan 25;848:131–139. doi: 10.1016/j.ejphar.2019.01.037

Table 3.

5-HT2C inverse agonists pIC50 and Imax values: Inositol phosphate reduction.

Inverse Agonist pIC50 Imax (% decrease from basal)
clozapine 6.89 ± 0.10 68 ± 4
SB 206553 7.77 ± 0.02 32 ± 5
CAT 7.17 ± 0.21 26 ± 4
MFP 7.62 ± 0.10 25 ± 3
mesulergine 7.62 ± 0.13 17 ± 2

n = 3.