Table 3.

ROC analyses of serum complement factors in pregnant women with SPE.

Variable	AUC	P value	95% CI
Early-onset SPE
C1q	0.814	<0.001	0.712–0.917
H	0.681	<0.001	0.556–0.806
Bb	0.743	<0.001	0.638–0.859
C3	0.803	<0.001	0.768–0.939
C4	0.812	<0.001	0.713–0.912
Combined*	0.916	<0.001	0.879–0.964
Late-onset SPE
C1q	0.805	<0.001	0.697–0.913
H	0.662	0.031	0.524–0.800
Bb	0.796	<0.001	0.680–0.911
C3	0.805	<0.001	0.761–0.906
C4	0.821	<0.001	0.699–0.943
Combined*	0.939	<0.001	0.901–0.977

SPE – severe pre-eclampsia;

^*ROC analysis with all the 5 complement factors: C1q, H, Bb, C3 and C4.