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. 2019 Sep 24;12:7877–7886. doi: 10.2147/OTT.S209307

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© 2019 Shen et al.

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Effects of BEX and DTX on cell cycle regulation of cyclins and CDK1. PC3 and DU145 cells were exposed to BEX (20 and 40 µM) and 10 nM (PC3) or 5 nM (DU145) DTX alone or in combination for 24h (A) or 48 h (B). The expression of cyclinD1, cyclinE2, cyclinB1, and CDK1 determined by Western blot analysis.