Table 1.

Antibacterial effects of isoxazoles 4a–i

Bacterial species		Products									Antibiotic
		4a	4b	4c	4d	4e	4f	4g	4h	4i	Gentamicin
1310	MIC	256	128	–	–	256	–	–	–	–	0.063
	MBC	512	256	–	–	512	–	–	–	–	0.063
1290	MIC	64	256	–	–	256	–	–	–	–	4
	MBC	128	512	–	–	512	–	–	–	–	4
1234	MIC	–	32	–	–	–	–	–	–	–	2
	MBC	–	64	–	–	–	–	–	–	–	8
1188	MIC	–	–	–	128	–	–	–	–	–	0.031
	MBC	–	–	–	512	–	–	–	–	–	0.063
1855	MIC	–	512	–	128	–	–	–	–	–	16
	MBC	–	2048	–	256	–	–	–	–	–	32
1399	MIC	–	–	–	32	–	–	–	–	–	8
	MBC	–	–	–	128	–	–	–	–	–	8
1768	MIC	512	128	256	256	–	64	–	–	128	0.5
	MBC	1024	256	1024	512	–	128	–	–	256	1
1297	MIC	32	64	32	64	32	32	256	32	64	2
	MBC	128	128	64	128	128	64	512	64	128	2
1445	MIC	–	256	–	64	–	–	–	–	256	2
	MBC	–	512	–	128	–	–	–	–	512	2
1240	MIC	256	512	–	–	–	–	–	–	–	1
	MBC	512	1024	–	–	–	–	–	–	–	1
1633	MIC	–	64	–	256	256	–	–	–	–	2
	MBC	–	128	–	512	512	–	–	–	–	2
1023	MIC	128	–	–	–	256	–	–	–	–	0.063
	MBC	512	–	–	–	512	–	–	–	–	0.063
1435	MIC	–	–	–	–	64	–	–	–	128	1
	MBC	–	–	–	–	128	–	–	–	512	2
1494	MIC	32	–	–	128	–	64	–	–	–	1
	MBC	64	–	–	512	–	128	–	–	–	1
1189	MIC	128	256	–	–	256	–	512	–	–	1
	MBC	512	1024	–	–	512	–	1024	–	–	1
1665	MIC	256	64	–	64	128	–	128	–	–	0.25
	MBC	512	64	–	128	512	–	256	–	–	4
1447	MIC	64	32	–	256	128	512	–	–	–	0.063
	MBC	128	32	–	512	512	512	–	–	–	0.125

–: No noticeable antibacterial effect at concentration of 10,240 μg ml⁻¹, MIC (μg ml⁻¹), MBC (μg ml⁻¹)