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Chronic stress increased the protein (A and B) and mRNA lever (E) of FoxO1 expression and its downstream genes, G6Pase (F) and PEPCK (G), and decreased the lever of p-FoxO1 protein (C) and p-FoxO1/FoxO1 (D), while as1842856 could reverse this effect except the protein and mRNA lever of FoxO1 expression. *p < 0.05, ***p < 0.001. Date presented as mean ± SEM, n = 6.
