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. Author manuscript; available in PMC: 2020 Jan 8.
Published in final edited form as: Nat Med. 2019 Jul 8;25(8):1274–1279. doi: 10.1038/s41591-019-0492-5

Extended Data Figure 8 -.

Extended Data Figure 8 -

Peripheral artery disease risk variants and mechanistic overlap with LAS and CAD

Venn diagram of each of the 19 PAD risk loci in a based on their association with PAD (two-sided PPAD < 5 ×10−8), CAD (P < 0.05), and LAS (P < 0.05). Each locus is depicted along with the plausible relationship to the underling causal risk factor separately by color. Loci names are based on the nearest genes; however, the causal gene(s) remains unclear for some associated loci and as such, the resultant annotation may prove incorrect in some cases.

Abbreviations: PAD, Peripheral Artery Disease; LAS, Large Artery Stroke; CAD, Coronary Artery Disease