Table 2.
Antimicrobial activities of the isolated compounds in the presence of reference antibioticsa at 1/4 of MIC as a function of microorganisms
| Microorganisms | Compound 1 alone | Compound 1 with ATBa at 1/4 of MIC | Compound 3 alone | Compound 3 with ATBa at 1/4 of MIC | Compound 4 alone | Compound 4 with ATBa at 1/4 of MIC | |||
|---|---|---|---|---|---|---|---|---|---|
| MIC | MIC | FIC | MIC | MIC | FIC | MIC | MIC | FIC | |
| E. coli | 32 | 8 | 0.25 | 128 | 16 | 0.125 | 256 | 16 | 0.0625 |
| S. flexneri | 16 | 8 | 0.5 | 64 | 16 | 0.25 | 128 | 4 | 0.0312 |
| S. aureus | 8 | 1 | 0.125 | 32 | 16 | 0.50 | 64 | 2 | 0.0312 |
| C. parapsilosis | 32 | 4 | 0.125 | 128 | 4 | 0.0312 | 16 | 2 | 0.125 |
| C. albicans | 64 | 4 | 0.0625 | 128 | 4 | 0.0312 | 16 | 1 | 0.0625 |
| C. neoformans | 16 | 2 | 0.125 | 32 | 2 | 0.0625 | 8 | 0.5 | 0.0625 |
MIC minimal inhibitory concentration, FIC fractional inhibitory concentration, ATB antibiotics
aFluconazole for yeasts and tetracycline for bacteria were tested at the concentration of MIC/4 on the corresponding microorganism