Table 1.
Namea | Source |
---|---|
Dacomitinib | LC Laboratories (MA, USA) |
Acetonitrile (ACN, HPLC-grade), ammonium formate (NH4COOH), poly ethylene glycol 300 (PEG 300), dimethyl sulfoxide (DMSO), potassium cyanide (KCN) and formic acid (HCOOH) | Sigma-Aldrich (USA) |
Tween 80 | Eurostar Scientific Ltd. (Liverpool, UK) |
Water (HPLC grade) | Milli-Q plus purification instrument (USA) |
Sprague–Dawley ratsb | The experimental animal care center at King Saud University (KSA) |
a All reference powders are of analytical grade and solvent are of HPLC grade
b The University’s Ethics Review Committee approved the animal experimental design