Table 1.

Non-organic ICG NPs

NP type	NP size (nm)	Tumor nature	In vitro model	In vivo model	Administration routes	References
Mesoporous silica NPs	50–100	–	–	Male Sprague Dawley rats	Intravenous injection	(49)
Mesoporous silica NPs	50–100	–	–	Male nude mice or Prague Dawley rats	Tail vein injection	(51)
rNGO-PEG	63	Tumor metastasis	Hela cells	Female BALB/c nude mice	Intravenous injection	(52)
Calcium phosphate NPs	80	–	Healthy human mononuclear cells, red-blood cells, platelets	Swiss albino mice	Tail vein injection	(53)
Calcium phosphate NPs	16	Breast tumor	–	Nude mice	Tail vein injection	(28)

Abbreviations: NP, Nano particle; rNGO-PEG, polyethylene glycol (PEG)ylated, reduced nano-graphene oxide nanocomposite.