Skip to main content
. 2019 Sep 17;5(3):150–166. doi: 10.1089/aivt.2019.0005

FIG. 11.

FIG. 11.

Changes in gene expression following exposure to AuNPs with or without a healthy or obese BC. Expression of mRNA was assessed relative to serum-free media control cells (untreated) (dotted line). Cells were grown to 90% confluency in a 96-well plate before exposure to 50 μg/mL AuNPs with no BC, a healthy BC, or an obese BC for 24 hours. Gene expression of TNF-α, CCL2, CXCL2, and GAPDH (control) was assessed through PCR to evaluate the inflammatory response induced by AuNP exposure. *Denotes statistical significance compared to the expression of the unexposed control, #denotes statistical significance compared to the AuNP with no BC, and †denotes statistical significance compared to the AuNP with a healthy BC. Comparisons were performed by one-way ANOVA with Tukey post hoc analysis (p < 0.05). GAPDH, glyceraldehyde 3-phosphate dehydrogenase; TNF-α, tumor necrosis factor-α.