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Cold exposure increases the expression and content of FGF21 and the content of FGF21 in the iBAT (A and B) and aBAT (C and D). Age- and weight-matched animals were either kept at room temperature or cold exposed (4°C) for 7 days. *p < 0.05 vs. Con. Unpaired, two-tailed t-test, n = 4–9.
