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. 2019 Aug 13;8(1):318–329. doi: 10.1080/21623945.2019.1649578

Figure 3.

Figure 3.

GSEA plot showing most enriched gene sets of all detected genes in the IRO subjects. The top-three most significant down-regulated enriched gene sets in the IRO subjects: kidney mesenchyme development (a), sex determination (b), positive regulation of synaspse assembly (c). The top-three most significant up-regulated enriched gene sets in the IRO subjects: leukocyte chemotaxis (d), chemokine-mediated signalling pathway (e), positive regulation of inflammatory response (f). GSEA: gene set enrichment analysis; NES: normalized enrichment score.