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. 2019 Aug 13;8(1):318–329. doi: 10.1080/21623945.2019.1649578

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© 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — KEGG pathway analysis of differentially expressed genes. Advanced bubble chart shows enrichment of DEGs in signalling pathways. Y-axis label represents pathway, and X-axis label represents rich factor (rich factor = amount of DEGs enriched in the pathway/amount of all DEGs in background gene set). Size and colour of the bubble represent amount of DEGs enriched in pathway and enrichment significance, respectively. KEGG: Kyoto Encyclopedia of Genes and Genomes; DEG: differentially expressed gene; FDR: false discovery rate.