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. 2019 Jul 11;8(1):280–291. doi: 10.1080/21623945.2019.1640007

Figure 6.

Figure 6.

The transcriptome and gene expressions in adipocytes overexpressing LMNA R133L.

(a). The transcriptome associated with adipocyte differentiation of 3T3-L1 cells. (b). Validation of the Affymetrix gene expression data in each of three clonal lines of 3T3-L1 cells transfected with control lentivirus, or lentivirus encoding Flag-tagged human LMNA wild-type or LMNA R133L, as revealed by qPCR using gene-specific primers (n = 3). Data are presented as means ± SDs. *P < 0.05 vs. Control; **P < 0.01 vs. Control. #P < 0.05 vs. LMNA wild-type; ##P < 0.01 vs. LMNA wild-type. (c). Ingenuity pathway, molecular functional, and biological process analyses of 3T3-L1 cells stably expressing LMNA wild-type or LMNA R133L.