Table 3.
Body weight and organ weights.
| Young |
Advanced-age |
|||
|---|---|---|---|---|
| SFD | WD | SFD | WD | |
| n | 5 | 5 | 9 | 10 |
| Body weight (g) | ||||
| Start | 26 ± 0.82 | 26 ± 0.54 | 31 ± 0.69 | 31 ± 0.80 |
| End | 39 ± 1.1 | 49 ± 0.86 *** | 41 ± 1.1 | 43 ± 1.8 |
| Body weight gain (g) | 13 ± 0.7 | 23 ± 0.67 ** | 9.8 ± 0.93 ° | 12 ± 1.6 °° |
| Caloric intake (kcal/day) | 16 ± 0.3 | 16 ± 0.1 | 15.5 ± 0.48 | 19.9 ± 2.06 |
| Organ weights (mg) | ||||
| SC adipose tissue | 780 ± 46 | 1591 ± 54 ** | 789 ± 139 | 858 ± 140 °° |
| GN adipose tissue | 2011 ± 203 | 2941 ± 114 ** | 1552 ± 207 | 1974 ± 270 ° |
| MES adipose tissue | 764 ± 93 | 1277 ± 29 ** | 612 ± 114 | 691 ± 101 ° |
| Liver | 1915 ± 202 | 3848 ± 342 ** | 1707 ± 84 | 2287 ± 249 * ° |
| Brown adipose tissue | 138 ± 11 | 278 ± 8 * | 103 ± 10.7 ° | 152 ± 13.3 * °°° |
| Adipocyte size (μm2) | ||||
| SC | 2753 ± 222 | 3550 ± 201 | 2720 ± 501 | 2425 ± 338 |
| GN | 3324 ± 422 | 4727 ± 340 * | 2411 ± 287 | 2108 ± 121 °°° |
| MES | 2624 ± 169 | 3366 ± 208 | 1584 ± 250 | 1684 ± 152 ° |
| Adipocyte density (x10−6/μm2) | ||||
| SC | 391 ± 39 | 287 ± 17 * | 493 ± 94 | 525 ± 82 ° |
| GN | 327 ± 52 | 220 ± 16 * | 475 ± 52 | 499 ± 32 °°° |
| MES | 404 ± 30 | 307 ± 21 | 675 ± 90 | 654 ± 81 ° |
Body weight and organ weights of young and advanced-age mice kept on either a SFD or a WD for 15 weeks. * = p < 0.05, ** = p < 0.01 and *** = p < 0.001 in SFD vs WD in either young or advanced-age mice. ° = p < 0.05, °° = p < 0.01 and °°° = p < 0.001 between young and advanced-age mice kept on the same diet. SFD = standard-fat diet, WD = western-type diet, SC = subcutaneous, GN = gonadal, MES = mesenteric.