Table 2.
Effect of 8 weeks treatment with sevelamer-carbonate on PWV (m/s)
| Treatment compared with baseline | β (95% confidence interval) | P-value | |
|---|---|---|---|
| All | |||
| Crude | −0.36 (−0.82 to 0.09) | 0.12 | |
| Model 1: crude + MAP | −0.24 (−0.58 to 0.10) | 0.17 | |
| Model 2: model 1 + FGF23 | −0.22 (−0.58 to 0.13) | 0.22 | |
| KI score <median | |||
| Crude | −0.71 (−1.43 to 0.01) | 0.05 | |
| Model 1: crude + MAP | −0.63 (−1.13 to −0.12) | 0.02 | |
| Model 2: model 1 + FGF23 | −0.58 (−1.04 to −0.12) | 0.01 | |
| KI score >median | |||
| Crude | 0.05 (−0.37 to 0.46) | 0.82 | |
| Model 1: crude + MAP | 0.13 (−0.22 to 0.48) | 0.47 | |
| Model 2: model 1 + FGF23 | 0.28 (−0.07 to 0.62) | 0.11 | |
Values of PWV following treatment compared with PWV baseline. GEE was used to analyse the difference between treatment and baseline PWV values. All PWV measurements (of all time points) were included in the model, depicted is only the difference between treatment and baseline PWV. Stratification for KI score above and below the median was performed.