Figure 4.

Concentrations of (A) total triiodothyronine (${\mathrm{T}}_3$), (B) total thyroxine (${\mathrm{T}}_4$), and lipids [(C) cholesterol, (D) triglycerides, (E) high-density lipoproteins (HDL), and (F) low-density lipoproteins (LDL)] in maternal serum following oral hexafluoropropylene oxide dimer acid (HFPO-DA) dosing from gestation days (GD) 14–18. Dam serum was collected on GD18 approximately 2 h after final oral dose. Data points represent individual replicates (control, $n=6$; treated, $n=3$), bars and whiskers represent $\text{mean}\pm$ standard error, and asterisks represent significant differences compared with control values using analysis of variance (*, $p<0.05$; **, $p<0.01$; ***, $p<0.001$; ****, $p<0.0001$). $<\text{DL}$, values below radioimmunoassay detection limit.