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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Wiley Interdiscip Rev RNA. 2018 Oct 28;10(1):e1513. doi: 10.1002/wrna.1513

Figure 5:

Figure 5:

(A) Hydrogen bonding pattern of modified or recoded s4U nucleosides following enrichment-free chemistry. (B) Example TimeLapse-seq tracks adapted from Schofield et al. 2018 for faster turnover (Ier3) and slower turnover (Srsf3) transcripts in MEF cells treated with 1 mM s4U for 1h.