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Effect of time, gender, age, hydroxyurea use and opioid consumption one-hour prior and clinical pain score on cold pain threshold of hand
| Variable | Estimate | SE | P value |
|---|---|---|---|
| Time (Acute Pain vs Baseline) | 137.05 | 53.62 | 0.02 |
| Gender (Female vs Male) | 155.48 | 117.32 | 0.20 |
| Age | 25.49 | 16.27 | 0.13 |
| Hydroxyurea (Yes vs No) | −293.38 | 180.07 | 0.12 |
| Opioid consumption (one-hour prior) | −9.20 | 14.91 | 0.54 |
| Clinical Pain Score | −19.43 | 25.72 | 0.46 |
Data were square transformed to ensure fit
SE: standard error
