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Effect of time, gender, age, hydroxyurea use and total opioid consumption and clinical pain score on mechanical pain threshold of foot
| Variable | Estimate | SE | P value |
|---|---|---|---|
| Time (Acute pain vs Baseline) | −0.82 | 0.22 | 0.0017 |
| Gender (Female vs Male) | −0.04 | 0.40 | 0.92 |
| Age | 0.03 | 0.05 | 0.54 |
| Hydroxyurea (Yes vs No) | −0.59 | 0.54 | 0.29 |
| Opioid consumption (total) Clinical Pain Score |
0.001 −0.08 |
0.002 0.08 |
0.57 0.32 |
Data were log transformed to ensure fit
SE: standard error
