Table 1. Characteristics of the studied patients (sLCL-1 to-14) with an iEBVL and one patient with a post-transplant lymphoproliferative disorder (PTLD-1).
Patient number | Age | Sex | Country of origin | Transplanted organ | Time from transplantation to iEBVL (in days) | EBV cop/ml WB |
Immunosuppressive regimen | PTLD | status at last FU |
---|---|---|---|---|---|---|---|---|---|
sLCL-1 | 66 | m | Germany | SCT | 26 | 3150 | CSA, MTX | - | alive |
sLCL-2 | 66 | m | Germany | SCT | 26 | 3150 | CSA, MTX | - | alive |
sLCL-3 | 56 | f | Germany | KT | 7456 | 9870 | CyA, ST | +a | alive |
sLCL-4 | 66 | f | Spain | KT | 1821 | 18600 | CSA, MMF, ST | - | alive |
sLCL-5 | 64 | m | Germany | SCT | 29 | 1000 | FK, MMF | - | dead (relapsed ALL) |
sLCL-6 | 66 | f | Germany | KT | 3024 | 1730 | ST | - | alive |
sLCL-7 | 68 | m | Germany | SCT | 26 | 2390 | CSA | - | alive |
sLCL-8 | 46 | f | Russia | SCT | 41 | 2330 | CSA | - | alive |
sLCL-9 | 64 | m | Germany | SCT | 35 | 2600 | CSA | - | alive |
sLCL-10 | 60 | f | Germany | KT | 2853 | 1920 | BELA/ST | - | alive |
sLCL-11 | 63 | m | Germany | SCT | 273 | 16200 | FK | - | alive |
sLCL-12 | 56 | f | Turkey | KT | 18 | 8450 | CSA, MMF, ST | - | alive |
sLCL-13 | 32 | m | Germany | KT | 22 | 22600 | CSA, ST | - | alive |
sLCL-14 | 37 | m | Germany | KT | 810 | 16400 | FK, MMF, ST | - | alive |
PTLD-1 | 49 | m | Germany | SCT | 27 | 10700 | CSA | + | dead (PTLD) |
iEBVL: increased EBV load, CSA: Cyclosporin A, MMF: Mycofenolate mofetil, FK: Tacrolimus, SIR: Sirolimus, AZA: Azathioprine, MTX: Methotrexate, BELA: Belatacept, KT: kidney transplantation, SCT: stem cell transplantation, ST: Steroid, m: male, f: female, cop: copies, WB: whole blood, FU: follow up, ALL: acute lymphoblastic leukemia.
aT-cell PTLD, not EBV-associated.