Figure 2.

Ceramides are correlated to glucose intolerance and insulin sensitivity in metabolically challenged mouse strains. Lipid-trait network showing plasma lipid correlations with five measured phenotypic traits. Correlations are represented as edges between lipid nodes and trait nodes. Only correlations with absolute value R > 0.4 are shown. Each trait node is depicted as a different color, and edges are colored according to the correlated trait. Edge width is proportional to correlation strength. Solid edge lines indicate positive correlations; dashed lines indicate negative correlations. Node label size is proportional to degree (total number of connections). Ceramide lipids that were chosen for further investigation based on their correlations to several mouse traits are boxed in red. Figure reproduced from [13].