Table 1.
Baseline Characteristics PHIV vs. non-HIV
| PHIV (n=344) |
Non-HIV (n=1805) |
p-value | |
|---|---|---|---|
| Females | 178 (52%) | 876 (49%) | 0.275 |
| Age (yrs, mean±SD) | 60±9.7 | 60±9.4 | 0.994 |
| Race | |||
| Hispanic | 132 (38%) | 756 (42%) | |
| African American | 139 (40%) | 632 (35%) | 0.167 |
| Others | 73 (21%) | 414 (23%) | |
| Cardiovascular risk factors | |||
| Diabetes | 134 (39%) | 628 (34%) | 0.139 |
| Hypertension | 221 (64%) | 1120 (62%) | 0.441 |
| Hyperlipidemia | 153 (44%) | 723 (39%) | 0.126 |
| Smoking | 162 (47%) | 821 (44%) | 0.583 |
| LVEF (%, mean±SD) | 47±12.0 | 48±12.4 | 0.168 |
| PASP (mmHg, mean±SD) | 47±9.2 | 40±9.0 | <0.001 |
| SBP (mmHg) | 141±27.5 | 139±27.1 | 0.211 |
| DBP (mmHg) | 78±18.3 | 79±18.0 | 0.346 |
| HR (bpm) | 85±21.2 | 83±21.5 | 0.113 |
| QRS duration (ms) | 116±25.3 | 114±25.6 | 0.184 |
| QTc duration (ms) | 435±30.4 | 432±30.7 | 0.100 |
| Serum creatinine (mg/dL) | 1.37±1.0 | 1.31±1.1 | 0.347 |
| BMI (kg/m2, mean±SD) | 27±5.8 | 34±5.9 | <0.001 |
| Sleep apnea | 101 (29%) | 478 (26%) | 0.270 |
| CAD | 162 (46%) | 581 (32%) | <0.001 |
| Cocaine use | 116 (34%) | 344 (19%) | <0.001 |
| Mode of cocaine administration | |||
| Intranasal | 33 (28%) | 107 (31%) | |
| Smoking | 45 (39%) | 151 (44%) | 0.263 |
| Intravenous | 38 (33%) | 86 (25%) | |
| HCV | 45 (13%) | 126 (7%) | <0.001 |
| HBV | 26 (8%) | 119 (6%) | 0.513 |
| HIV parameters | |||
| CD4 count cells/mm3(mean±SD) | 336±244 | ||
| VL <200 copies/mL | 221 (64%) | ||
| ART prescription | 313 (91%) | ||
| Duration of ART prescription (yrs), median (IQR) | 9 (4–16) | ||
| Duration of HIV (yrs), median (IQR) | 9 (4–16) | ||
| Cardiovascular Medications | |||
| Beta blocker | 293 (85%) | 1573 (87%) | 0.321 |
| ACE/ARB | 286 (83%) | 1544 (86%) | 0.251 |
| Spironolactone | 40 (12%) | 187 (10%) | 0.483 |
| Furosemide | 263 (77%) | 1444 (80%) | 0.136 |
BMI= body mass index, LVEF = left ventricular ejection fraction, PASP= pulmonary artery systolic pressure, CAD= coronary artery disease, ICD= implantable cardioverter defibrillator, HCV- hepatitis C virus infection, HBV= hepatitis B virus infection, ACE I= angiotensin converting enzyme inhibitor, ARB= angiotensin receptor blocker, ART = antiretroviral therapy.VL= viral load.