Figure 7. Model of MuSC behavior in overloaded muscle.

(A) Distinct environments for MuSC proliferation between regenerating and overloaded muscle. (B) Essential roles of HeyL in MuSC proliferation in overloaded muscle.

Figure 7—figure supplement 1. Kinetics of MuSC behavior in overloaded muscle.

(A) MuSC behavior in overloaded muscle. (B) Frequency of EdU⁺Pax7⁺ cells among Pax7⁺ cells. After tenotomy, EdU was injected until mice were sacrificed. (C) Gradual increases in the number of new MuSC-derived myonuclei up to 14 days after tenotomy. After tenotomy, EdU was injected until mice were sacrificed.