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. 2018 Sep 24;58(7):2767–2778. doi: 10.1007/s00394-018-1826-7

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 4 — Elevated SCFA levels in fecal samples of patients after synbiotic treatment. Fecal samples were analyzed by HPLC. A significant elevation in fecal acetate and butyrate levels (µmol/g) before (white) vs. after synbiotic treatment (grey) were found. Acetate (101 [79–133] vs. 202 [68–252]; p = 0.007) and butyrate content (27 [14–35] vs. 40 [25–67]; p = 0.037) (median [Q1–Q3]; Mann–Whitney U test or t test to compare non-gaussian and gaussian variables. Boxplots according to Tukey)