Table 3.
Effect of the Multifactorial Intervention on physical function capacity stratified by a frailty degree according to the Clinical Frailty Scale
Fit, Stable, managing well (CFS 1–3), n=41 | Vulnerable (CFS 4–6), n=48 | Any grade of Frailty (CFS 7–9), n=23 | p for trend | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Before | After | Difference (95% IC) | p | Before | After | Difference (95% IC) | p | Before | After | Difference (95% IC) | p | ||
SPPB a, mean (SD) | 8.43 | 9.68 | 1.25 | <0.001 | 7.13 | 8.67 | 1.54 | <0.001 | 6.52 | 8.21 | 1.70 | <0.001 | 0.279 |
(2.05) | (2.08) | (0.81 – 1.69) | (2.02) | (1.95) | (.99 – 2.09) | (1.90) | (1.76) | (1.04 – 2.35) | |||||
Gait speed (m/sec), mean (SD) | 0.77 | 0.86 | 0.08 | <0.001 | 0.71 | 0.78 | 0.07 | 0.005 | 0.60 | 0.69 | 0.09 | <0.001 | 0.940 |
(0.18) | (0.17) | (0.05 – 0.12) | (0.21) | (0.17) | (0.02 – 0.11) | (0.14) | (0.16) | (0.04 – 0.13) | |||||
Balance impairment, % (n) | 31.7 | 14.6 | 53.8 | 0.001 | 52.1 | 25.0 | 52.0 | 0.009 | 47.8 | 21.7 | 54.5 | 0.043 | 0.540 |
(13) | (6) | (7) | (25) | (12) | (13) | (11) | (5) | (6) | |||||
Chair stand test (sec), mean (SD) | 18.28 | 13.97 | −4.32 | 0.002 | 25.58 | 18.16 | −7.43 | <0.001 | 23.37 | 19.83 | −3.55 | 0.235 | 0.352 |
(9.99) | (4.85) | (−6.89 – −1.75) | (15.91) | (11.91) | (−11.45 – −3.41) | (13.92) | (13.84) | (−9.56 – −2.47) |
SD: standard deviation; a. SPPB: Short Physical Performance Battery, range from 0 to 12; The Analysis of variance (ANOVA) and Jonckheere-Terpstra trend test were used for continuous variables as appropriated and Chi-Square for categorical variables.