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Time trend of total WOMAC index over the course of follow-up (baseline and after 1, 6, 12, and 24 months) stratified by treatment (hyaluronic acid [HA] 1,500–3,200 kDa, hylan G-F 20, NSAIDS as controls [CTRLS]) and radiological grades II, III, and IV according to the Kellgren-Lawrence classification (A, K-L 2; B, K-L 3; C, K-L 4). Bars refer to standard error.
