Table 1.
Demographic and clinical characteristics of patients stratified by treatment, at time of recruitment. Continuous variables are summarized as mean ± SD, categorical variables as percentage (absolute frequency).
| Baseline | Hyaluronic acid 1,500–3,200 kDa | HYLAN G-F 20 | CTRLS | Overall p-value |
|---|---|---|---|---|
| (N = 43) | (N = 79) | (N = 20) | ||
| Age (years) | 61.2 ± 14.8 | 63.0 ± 13.1 | 60.4 ± 11.1 | 0.647 |
| Age% (>65ys) | 39.5 (17) | 50.6 (40) | 40.0 (8) | 0.429 |
| Gender F %(N) | 51.2 (22) | 62.0 (49) | 55.0 (11) | 0.492 |
| Weight (kg) | 76.8 ± 12.7 | 72.6 ± 13.1 | 73.6 ± 10.2 | 0.215 |
| Height (cm) | 169.6 ± 9.9 | 166.2 ± 8.8 | 169.2 ± 7.4 | 0.105 |
| BMI (Kg/m2) | 26.6 ± 3.3 | 26.2 ± 3.6 | 25.7 ± 2.7 | 0.546 |
| BMI% (>25 Kg/m2) | 60.5 (26) | 55.7 (44) | 70.0 (14) | 0.498 |
| Disease duration% (≥5ys) | 20.9 (9) | 27.8 (22) | 25.0 (5) | 0.703 |
| K-L rating score %(N) | 0.322 | |||
| Grade 2 | 32.6 (14) | 22.8 (18) | 15.0 (3) | |
| Grade 3 | 58.1 (25) | 57.0 (45) | 60.0 (12) | |
| Grade 4 | 9.3 (4) | 20.3 (16) | 25.0 (5) |