Table 4.
Mean values and related standard errors (SE) of NSAID/analgesic consumption (days/month) within each group of treatment.
| Therapy | Mean (SE) | Overall p-value | p-value (ti vs. t0) |
|---|---|---|---|
| Hyaluronic acid 1,500–3,200 kDa | <0.0001 | ||
| Baseline | 9.7 (1.4) | − | |
| 1 mth | 5.0 (1.1) | 0.003 | |
| 6 mths | 4.5 (1.1) | 0.0001 | |
| 12 mths | 3.2 (0.9) | <0.0001 | |
| 24 mths | 3.6 (1.0) | <0.0001 | |
| Hylan G-F 20 | <0.0001 | ||
| Baseline | 9.1 (1.1) | − | |
| 1 mth | 5.7 (1.0) | 0.001 | |
| 6 mths | 3.7 (0.7) | <0.0001 | |
| 12 mths | 3.5 (0.7) | <0.0001 | |
| 24 mths | 3.9 (0.7) | <0.0001 | |
| Controls | 0.06 | ||
| Baseline | 8.0 (1.8) | − | |
| 1 mth | 15.9 (2.4) | <0.01 | |
| 6 mths | 11.5 (1.6) | 0.157 | |
| 12 mths | 11.4 (1.6) | 0.152 | |
| 24 mths | 11.7 (1.3) | 0.091 |