Figure 6.

Increased Pax7 nuclei in VKD^Het muscle. TA cross-sections from control (A) and VKD^Het (B) mice were labeled with Pax7 (red) and DAPI (green). While the percentage of muscle fibers with Pax7+ nuclei is unchanged at 4 months of age, there is a significant increase in the percentage of Pax7+ nuclei in 17 month-old VKD^Het mice compared to controls (C). Represented as mean ± SEM. Representative images from 17 month-old samples. Scale bar = 50 μm. Only male mice were used for these experiments. Control n = 4; VKD^Het n = 4 in each age group. Black circles represent individual data points. *p < 0.05.