| 1 Pregnancy loss |
3 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
| 1.1 IVIG (+/‐ heparin and aspirin) versus heparin (unfractionated or LMW) and aspirin |
2 |
56 |
Risk Ratio (M‐H, Random, 95% CI) |
2.71 [0.86, 8.57] |
| 1.2 IVIG versus prednisone and aspirin |
1 |
82 |
Risk Ratio (M‐H, Random, 95% CI) |
0.94 [0.42, 2.12] |
| 2 Premature delivery |
3 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
| 2.1 IVIG (+/‐ heparin and aspirin) versus heparin (unfractionated or LMW) and aspirin |
2 |
56 |
Risk Ratio (M‐H, Random, 95% CI) |
1.46 [0.19, 11.17] |
| 2.2 IVIG versus prednisone and aspirin |
1 |
82 |
Risk Ratio (M‐H, Random, 95% CI) |
0.55 [0.08, 3.68] |
| 3 Adverse pregnancy outcome (pregnancy loss or preterm labour) |
3 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
| 3.1 IVIG (+/‐ heparin and aspirin) versus heparin (unfractionated or LMW) and aspirin |
2 |
56 |
Risk Ratio (M‐H, Random, 95% CI) |
2.38 [1.24, 4.58] |
| 3.2 IVIG versus prednisone and aspirin |
1 |
82 |
Risk Ratio (M‐H, Random, 95% CI) |
0.85 [0.42, 1.72] |
| 4 IUGR with interventions |
2 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
| 4.1 IVIG (+/‐ heparin and aspirin) versus heparin (unfractionated or LMW) and aspirin |
1 |
16 |
Risk Ratio (M‐H, Random, 95% CI) |
0.43 [0.06, 3.28] |
| 4.2 IVIG versus prednisone and aspirin |
1 |
82 |
Risk Ratio (M‐H, Random, 95% CI) |
0.0 [0.0, 0.0] |
| 5 Adverse pregnancy outcome (pregnancy loss or IUGR) |
2 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
| 5.1 IVIG (+/‐ heparin and aspirin) versus heparin (unfractionated or LMW) and aspirin |
1 |
16 |
Risk Ratio (M‐H, Random, 95% CI) |
0.43 [0.06, 3.28] |
| 5.2 IVIG versus prednisone and aspirin |
1 |
82 |
Risk Ratio (M‐H, Random, 95% CI) |
0.94 [0.42, 2.12] |
| 6 Neonatal intensive care admission |
2 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
| 6.1 IVIG (+/‐ heparin and aspirin) versus heparin (unfractionated or LMW) and aspirin |
2 |
56 |
Risk Ratio (M‐H, Random, 95% CI) |
0.65 [0.09, 4.69] |
| 6.2 IVIG versus prednisone and aspirin |
0 |
0 |
Risk Ratio (M‐H, Random, 95% CI) |
0.0 [0.0, 0.0] |
| 7 Caesarean section |
1 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
| 7.1 IVIG (+/‐ heparin and aspirin) versus heparin (unfractionated or LMW) and aspirin |
1 |
40 |
Risk Ratio (M‐H, Random, 95% CI) |
2.73 [0.12, 63.19] |
| 7.2 IVIG versus prednisone and aspirin |
0 |
0 |
Risk Ratio (M‐H, Random, 95% CI) |
0.0 [0.0, 0.0] |
| 8 Weighted mean difference for birthweight |
3 |
|
Mean Difference (IV, Random, 95% CI) |
Subtotals only |
| 8.1 IVIG (+/‐ heparin and aspirin) versus heparin (unfractionated or LMW) and aspirin |
2 |
56 |
Mean Difference (IV, Random, 95% CI) |
‐56.34 [‐195.01, 82.33] |
| 8.2 IVIG versus prednisone and aspirin |
1 |
82 |
Mean Difference (IV, Random, 95% CI) |
351.0 [114.07, 587.93] |
