| Methods |
RCT.
Open label.
Active controlled. |
| Participants |
36 people with POAG.
Racial constitution is not reported.
Inclusion criteria: IOP above 21 mmHg on 2 occasions, optic disc cupping supportive of a diagnosis of glaucoma, visual field loss typical of nerve fibre bundle damage.
Exclusion criteria: coexisting ocular pathlogy. |
| Interventions |
Timolol 0.25% or 0.5% twice daily (adjustment according to IOP).
Pilocarpine 2% or 4% twice daily (adjustment according to IOP). |
| Outcomes |
IOP control.
Progression rate of visual field score (Goldmann and Friedmann static suprathreshold perimetry). |
| Notes |
Study duration 17 months. Due to early miotic intolerance, the follow‐up groups comprised 14 patients on pilocarpine, as compared to 22 patients on timolol. The number of originally included subjects is not stated.
Miosis may have influenced the visual field results.
The paper does not state whether data where averaged for both eyes or represent only one eye per patient. |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment? |
Unclear risk |
B ‐ Unclear |
