Skip to main content
. 2019 Sep 30;5:138. doi: 10.1038/s41420-019-0219-x

Fig. 6. GK is essential in the control of pancreatic β cell viability in response to energy stress.

Fig. 6

a Representative blots showing the comparative endogenous levels of GK protein comparing MIN6 and HEK cells. Data are presented as mean ± SD. *P < 0.05, t-test (two-tailed, unpaired), represents the comparison of GK/tubulin ratios in MIN6 with HEK cells. b Representative experiment (n = 2) in MIN6 with or without the transfection of the phospho-mimetic mutant form of BAD (BADS155D) after the treatment with the different energetic stressor for 24 h. c BCL2/tubulin ratios are represented as mean ± SD. *P < 0.05, t-test (two-tailed, unpaired), and compares the value of either 2DG or glucose deprivation between MIN6 with or without the transfection with the construct BAD S155D. d Representative experiment in HEK cells (n = 2) with or without the transfection of the phospho-mimetic mutant form of BAD (BADS155D) after the treatment with the energetic stressors for 24 h. e Data are presented as mean ± SD. *P < 0.05