| Al‐Sabah 2008 |
Cost effectiveness study. Not an RCT. |
| Andrews 2005 |
Not an RCT. Retrospective observation study. |
| Avgerinos 2005 |
Randomised controlled trial in participants with Peptic ulcer bleeding with outcome being serial gastric PH measurements over 24 hours, in response to treatment with somatostatin, PPI and placebo. |
| Bai 1995 |
Restricted to participants with bleeding from peptic ulcer and acute gastric mucosal lesions. Randomised after endoscopy. |
| Bajaj 2007 |
RCT comparing oral and IV PPI in NVUGIB. Does not satisfy the inclusion criteria of this review. |
| Brunner 1990 |
Limited to peptic ulcer bleeding. Randomisation after endoscopy. |
| Cheng 2005 |
Randomised after endoscopy. Comparison between low and high dose IV PPI. participants with peptic ulcer bleeding and comorbid illness. |
| Chu 1993 |
Restricted to peptic ulcer bleeding participants only and randomisation after endoscopy. |
| Colin 1993 |
Not randomised controlled trial. |
| Costamagna 1998 |
Randomised after endoscopy. |
| Dovas 1992 |
Unable to gain copy of publication. |
| Elphick 2007 |
Not an RCT. Letter to the editor. |
| Fasseas 2001 |
Restricted to endoscopically verified participants and only gastric ulcers, duodenal ulcers and erosions were included. |
| Felder 1998 |
Restricted to peptic ulcer bleeding participants only. |
| Fried 1999 |
Randomised after endoscopy. Restricted to peptic ulcer bleeding participants only. |
| Gao 1995 |
Unclear when randomisation took place. |
| Goletti 1994 |
Control group not being either placebo or H2RA alone; compared omeprazole alone versus the combination of ranitidine and endoscopic haemostatic therapy. Restricted to participants with ulcers or haemorrhagic gastritis. Randomisation post endoscopic diagnosis. |
| Hasselgren 1998 |
Study with main outcome of intra gastric PH studies. Limited to Peptic ulcer bleeding. |
| Hulagu 1994 |
Abstract publication, the trial was subsequently published in full (Hulagu 1995). |
| Hung 2007 |
Randomized post endoscopy in peptic ulcer bleeding. |
| Jensen 2006 |
RCT on bleeding peptic ulcer participants. Randomized post endoscopic haemostasis. |
| Keyvani 2006 |
Not an RCT. Retrospective observation study. |
| Kim 2007 |
Randomisation post endoscopy. RCT comparing oral PPI to endoscopic haemoclipping in peptic ulcer bleeding. Does not satisfy the inclusion criteria of this review. |
| Lau 2005 |
Abstract publication with results for Peptic ulcer disease participants only. The trial was subsequently published in full (Lau 2007). |
| Lee 2003 |
Cost effectiveness study. |
| Lin 2007 |
Not an RCT. Letter to the Editor. |
| Liu 2002 |
Randomised after endoscopy. Restricted to duodenal ulcer participants. |
| Maculotti 1995 |
Designed to assess healing rates. Not reporting any of the outcomes pre‐determined in this systematic review. Randomisation post endoscopy. |
| Munkel 1997 |
Restricted to peptic ulcer bleeding participants only. Randomisation post endoscopy. |
| Murthy 2007 |
Not an RCT. Retrospective review of oral PPI versus IV PPI in peptic ulcer bleeding post endoscopic haemostasis. |
| Nehme 2001 |
Randomised after endoscopy. |
| Orti 1995 |
Restricted to participants suspected to have bleeding from peptic origin. It was not clear from the paper if the authors ascertained this before randomisation. Communications to obtain further details are ongoing. |
| Perez Flores 1994 |
Randomisation post endoscopy, restricted to participants with peptic ulcer bleeding |
| Savides 2001 |
Randomised after endoscopy, restricted to peptic ulcer bleeding. |
| Schaffalitzky 2007 |
Not an RCT. Letter to the editor. |
| Scheurlen 2000 |
Restricted to peptic ulcer bleeding participants only, not RCT. |
| Schonekas 1999 |
Restricted to peptic ulcer bleeding participants only; control group not either placebo or H2RA alone; compared two different regimens of PPI. |
| Srinath 1997 |
Not a randomised controlled trial. This article was a comment on another RCT (Khuroo 1997). |
| Sung 2003 |
Randomisation post endoscopy. participants with visible vessel and adherent clot. |
| Sung 2008 |
Randomisation post endoscopy. participants with Peptic ulcer bleeding only. |
| Tran 2007 |
Not an RCT. Letter to the editor. |
| Tsoi 2008 |
Not an RCT. Cost effectiveness study based on the data from the Lau study (Lau 2007). |
| Udd 2001 |
Control group not being either placebo or H2RA alone; compared to intravenous regimens of omeprazole at different doses. |
| Uribarrena 1994 |
Selected participants with bleeding from gastric ulcer, duodenal ulcer, erosions and peptic oesophagitis only. Participants with bleeding from non‐peptic sources were excluded from the analysis. |
| Wei 2007 |
Randomization post endoscopic haemostasis. participants with peptic ulcer bleeding |
| Wu 2001 |
Unable to gain copy of publication. |
| Xuan 2003 |
Randomisation after endoscopy. |
| Yilmaz 2006 |
Randomization post endoscopy. participants with peptic ulcer bleeding with low risk stigmata. |
| Zargar 2006 |
Randomization post endoscopy. participants with peptic ulcer bleeding. |