Skip to main content
. 2019 Sep 24;10:1182. doi: 10.3389/fphys.2019.01182

TABLE 1.

Baseline characteristics of patients with dilated cardiomyopathy (n = 21).

Baseline characteristics Cell type P-value

Allogeneic (n = 10) Autologous (n = 11)
Age at injection (years) 58.3 (7.82) 55.909 (10.65) 0.99
Gender
 Male 7 (70%) 6 (54.5%) 0.5
 Female 3 (30%) 5 (45.5%) 0.5
 Ethnicity: Hispanic or Latino 1 (10%) 6 (54.5%) 0.03
 Race: White 8 (80%) 5 (45.5%) 0.1
 Race: Black 1 (10%) 0 (0%) 0.3
 History of hypertension 4 (40%) 2 (18.2%) 0.3
New York heart association class
 Class I – No limitation 2 (20%) 4 (36.4%) 0.4
 Class II – Slight limitation of physical activity 5 (50%) 6 (54.5%) 0.8
 Class III – Marked limitation of physical activity 3 (30%) 1 (9.1%) 0.2
 History of congestive heart failure 5 (50%) 5 (45.5%) 0.8
 History of Valvular heart disease 1 (10%) 0 (0%) 0.3
 History of smoking 7 (70%) 4 (36.4%) 0.3
 History of diabetes 0 (0%) 1 (9.1%) 0.3
 Peak VO2 (mL/kg/min) 17.23 ± 6.8 15.91 ± 5.94 0.6
 Six minute walk test (meters) 437.78 m ± 66.95 425.27 m ± 74.66 0.7
 Forced expiratory volume in one second (%) 2.43% (0.51) 2.41% (0.9) 0.9
 MLHF: Median (IQR) 44.6 (24.75–68) 39 (21–67) 0.6
LV size and function
 Ejection fraction (%) 24.4% ± 5.52 21% ± 7.68 0.3
 Left ventricular end diastolic volume (mL): Median (IQR) 253.8 mL (225.2–272.45) 193.2 mL (172.55–330.9) 0.7
 Left ventricular systolic volume (mL): Median (IQR) 196.15 mL (171.73–219.95) 164 mL (125.5–290.8) 0.7
 End diastolic diameter (cm): Median (IQR) 7 cm (6.63–7.18) 6.1 cm (5.85–7.65) 0.9
Biomarkers
 EPC-CFUs 3 ± 2 colonies 5 ± 3 colonies 0.08
 TNFα 24.5 ± 5.6 pg/mL 25.3 ± 13.3 pg/mL 0.9

Patient data are broken down by cell treatment, allogeneic (n = 10) vs. autologous (n = 11). Values are presented as n, n (%), or mean ± standard deviation. T-Tests and Chi-squared tests were used to compare groups, and statistically significant differences are indicated by bolding and an asterisk.