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. 2019 Sep 26;14:7861–7878. doi: 10.2147/IJN.S215935

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© 2019 Bewersdorff et al.

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Comparison of the amount of bound proteins in the corona of the respective NGs using the Top 3 approach.

Notes: Proteins in the NG coronas were identified using LC-MS/MS and abundancies were determined using the Top 3 approach. The intensity for each protein is obtained by summing up the intensities of the three most intense unique peptides for that protein. Based on that, total protein intensities for each NG were determined.

Abbreviations: NGs, nanogels; LC-MS/MS, liquid chromatography-tandem mass spectrometry; A.U., arbitrary unit; PHPMA, poly(N-(2-hydroxypropyl)methacrylamide).