Mira 2003.
Study characteristics | ||
Methods | Randomised, double‐blind, parallel trial | |
Participants | 144 patients (81 Ménière's disease, 63 BPPV) 41 Ménière's patients allocated to betahistine group, 40 to placebo |
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Interventions | Betahistine dihydrochloride 16 mg twice daily versus placebo (identical in colour, weight and flavour) | |
Outcomes | Vertigo (grade I). Reduced with betahistine Quality of life (grade III). Improved activity levels at 2 and 3 months with betahistine |
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Notes | Allocation bias: low Attrition bias: medium | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment (selection bias) | Low risk | A ‐ Adequate |