| Study | Reason for exclusion |
|---|---|
| Averkov 1993 | Not all patients treated with ASA |
| Bodo 1995 | Not a randomized controlled trial |
| Borja 2000a | Not a randomized controlled trial |
| Borja 2000b | Not a randomized controlled trial |
| Borja 2000c | Not a randomized controlled trial |
| Brown 1964 | Patients had ST‐segment elevation MI |
| Charvat 1989 | Not all patients treated with ASA |
| Cohen 1993 | Unclear from results to which study group participants had been randomized. Attempts to communicate with authors unsuccessful. |
| Cohen 2003 | Heparin not compared versus placebo |
| Collins 1996 | Not a randomized controlled trial |
| COMPARE 2010 | Patients not compared to placebo |
| Correia 1995 | Patients not compared to placebo |
| CREATE 2005 | Patients had ST‐segment elevation MI |
| FAMI 2000 | No control group in the acute phase of the study |
| Ferguson 1999 | Not a randomized controlled trial |
| FRISC II 1999 | Patients randomized greater than 72 hrs after most recent chest pain |
| Fujita 1988 | Not the research question |
| GISSI‐2 1990 | Patients had ST‐segment elevation MI |
| Gorski 1993 | Not a randomized controlled trial |
| Goy 1999 | Not a randomized controlled trial |
| Gulba 1992 | Not a randomized controlled trial |
| Hasselblad 1998 | Not a randomized controlled trial |
| Huber 1989 | Not all patients treated with ASA |
| Hurtado 1984 | Patients had ST‐segment elevation MI |
| Jaffrani 1993 | Not a randomized controlled trial |
| Kaul 2000 | Not a randomized controlled trial |
| Kontny 2001 | Not a randomized controlled trial |
| Massel 2002 | Not a randomized controlled trial |
| Mattioli 1999 | Heparin not compared versus placebo |
| Milonig‐Ganner 1989 | Not a randomized controlled trial |
| Moise 1994 | Not a randomized controlled trial |
| Montgomery 1995 | Not a randomized controlled trial |
| Nardelli 1991 | Not a randomized controlled trial |
| OASIS‐6 2006 | Patients had ST‐segment elevation MI |
| Ocampo 1998 | Heparin not compared versus placebo |
| Oldgren 2008 | Not a randomized controlled trial |
| Oler 1996 | Not a randomized controlled trial |
| Peterson 2001 | Not a randomized controlled trial |
| PURSUIT 2001 | Not the study question |
| Raschke 1993 | Not the study question |
| Rubio‐Terres 2001 | Not a randomized controlled trial |
| Sayen 1982 | Not a randomized controlled trial |
| Serneri 1988 | Outpatient setting |
| Serneri 1990 | Not all patients treated with ASA; only inpatients were admitted into the study |
| Serneri 1995 | Not all patients treated with ASA |
| Spodick 1989 | Not a randomized controlled trial |
| Tanajura 1993 | Outpatient setting, no patients with acute coronary syndromes |
| TETAMI 2000 | Not a randomized controlled trial |
| Théroux 1993 | Not all patients treated with ASA |
| Thieuleux 1985 | Not a randomized controlled trial |
| Umans 1997 | Not a randomized controlled trial |
| Violaris 1991 | Not a randomized controlled trial |
| Wallentin 1997 | Not a randomized controlled trial |
| Wallis 1991 | Not a randomized controlled trial |
ASA ‐ aspirin MI ‐ myocardial infarction