FIGURE 4.

Area-specific daily SWS delta power dynamics is different in young and older mice. (A) Estimated mean delta power in SWS at each hour of the day for the frontal electrode (left panel), the somatosensory anterior electrode (middle panel), and somatosensory posterior electrode (right panel) for young (black circles, n = 99 days from eight mice) and older mice (gray circles, n = 67 days from nine mice). Printed values are estimated marginal means computed in two independent mixed linear models (one per light or dark phase) using factors of age, electrode, and time of the day. (B) Mean SWS delta power in frontal cortex (red), somatosensory anterior cortex (green), and somatosensory posterior cortex (black) for 24 h (left panel), light phase (middle panel), and dark phase (right panel) for young (bright colors) and older (light colors) mice. Error bars indicate the 95% confidence interval. Significant statistical differences are indicated by asterisk, ^∗p < 0.05, ^∗∗p < 0.01, ^*⁣∗∗p < 0.001.