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. 2019 Aug 23;84(4):909–917. doi: 10.1007/s00280-019-03916-0

Table 4.

Clinical outcomes including best overall response, progression free survival, and overall survival

Cohort All
Level − 1 Level 1
N % N % N %
All 4 100.0 7 100.0 11 100.0
Best overall response
 Inevaluable 0 0.0 1 14.3 1 9.1
 Progressive disease 4 100.0 4 57.1 8 72.7
 Stable disease 0 0.0 2 28.6 2 18.2
Median OS (95% CI) in months 2.76 1.25–4.21 7.23 2.04–10.0 4.21 2.04–9.46
Median PFS (95% CI) in months 1.71 0.92–1.84 1.91 0.95–9.46 1.84 0.95–4.14